Diphtheria: Medical Significance Of Its Clinical Presentations And Complications

Funom Makama By Funom Makama, 1st Apr 2014 | Follow this author | RSS Feed
Posted in Wikinut>Health>General Health>Diseases & Infections

These depend on the primary site of involvement, duration of the illness, systemic effects of the toxin, and resistance of the host. The disease starts with sore throat, low grade fever, headache, malaise, vague aches and pains and catarrhal symptoms. As the disease progresses, tachycardia, nausea, vomiting, pallor and weakness follow.

Clinical Manifestations Of Diphtheria

Pharyngeal diphtheria: It is the commonest form and the membrane is present over the tonsils and pharynx. Gross cervical lymphadenopathy (described as bull neck) is evident and respiratory obstruction may develop, especially in children. In severe cases, circulatory collapse occurs. Local effects of the toxin lead to paralysis of the palate and pharynx. The term “malignant diphtheria” is given to the condition characterized by marked edema of the submandibular areas and anterior part of the neck. There is moderate leucocytosis (14,000 to 16,000/cu.mm) with polymorphs forming 60 to 80%.

Laryngeal diphtheria: This forms 25% of the cases. It produces respiratory obstruction early, which may be fatal. The clinical features include barking cough, hoarseness, dyspnea, stridor and cyanosis. Infants with laryngeal diphtherias may refuse to suck the breasts due to choking.

Nasal diphtheria: It occurs in 2 to 3% of cases. The membrane is limited to the septum or turbinates and it is usually unilateral. The condition may present with a foul smelling serosanguineous nasal discharge or frank epistaxis.

Cutaneous diphtheria: Corynebacterium diphtheria cannot penetrate the intact skin but it gains entry through wounds, burns, or abrasions. It causes ulceration. The typical ulcer is usually punched out and 0.5cm or more in size. Sometimes, it may resemble a nonspecific ulcer. In the early stage, the ulcer is covered by a grayish yellow or brownish membrane. There may be coexistent pharyngeal diphtheria in 20% of cases.

Other sites of lesion are the conjunctiva, vulva, vagina, uterine cervix, bladder, urethra, penis, middle ear, buccal mucous membrane and esophagus.

Complications Of Diphtheria

Mechanical obstruction of airway by the spreading membrane is a dreaded complication. The other complications are due to the systemic effects of the toxin. The incidence and severity of toxic manifestations increase in proportion to the extent of the membrane.

Toxic complications are most pronounced in the heart and motor nerves. Though, 60% of patients have pathological lesions in the heart, only 10 to 20% manifest clinically. Myocarditis should be suspected if there is variation in the intensity of heart sounds, systolic murmurs, conduction defects, atrial fibrillation, ventricular ectopic beats or ventricular tachycardia. Sudden death may occur due to ventricular fibrillation. Congestive failure and cardiac dilatation are less common. In infants and young children, vomiting may be an early symptom of cardiac involvement. Though electrocardiographic changes are nonspecific, the presence of abnormalities strongly suggests myocarditis.

Toxic peripheral neuritis develops 2 to 6 weeks, after the primary lesion. Third, sixth, seventh, ninth and tenth cranial nerves are commonly affected. Palatal and pharyngeal paralysis may occur as early as the third day. External ophthalmoplegia and paralysis of accommodation are frequent. Motor weakness may involved the limbs or respiratory muscles. Ascending polyneuritic type of lesions may follow 2 to 3 months after the acute attack of diphtheria. Though there are pathological lesions demonstrable in the adrenals, most cases do not manifest clinically.

For more Health Articles, visit the following links:
1. Fitness And Exercise From A Doctor’s Perspective: Maintaining The Lifestyle
2. Special Types Of Anemia: Sideroblastic Anemias And Paroxysmal Nocturnal Hemoglobinuria (PNH)
3. Diphtheria: The Health Significance Of Its Clinical Diagnosis And Phases Of Treatment

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author avatar 威哥王
12th Sep 2014 (#)

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author avatar 威哥王
12th Sep 2014 (#)

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author avatar 威哥王
12th Sep 2014 (#)

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12th Jan 2020 (#)


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<a href="https://companymoversinjeddah.wordpress.com/2018/12/12/%d8%b4%d8%b1%d9%83%d8%a7%d8%aa-%d9%86%d9%82%d9%84-%d8%b9%d9%81%d8%b4-%d9%88%d8%a7%d8%ab%d8%a7%d8%ab-%d8%a8%d8%a7%d9%84%d8%a8%d8%a7%d8%ad%d9%87/">شركات نقل عفش واثاث بالباحه</a>
<a href="https://companymoversinjeddah.wordpress.com/2018/12/12/start-moving-company-to-khamis-mushit/">وسائل نقل العفش بخميس مشيط</a>

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author avatar شركة نقل اثاث بالرياض
12th Jan 2020 (#)


http://emc-mee.com/blog.html شركات نقل العفش
اهم شركات كشف تسربات المياه بالدمام كذلك معرض اهم شركة مكافحة حشرات بالدمام والخبر والجبيل والخبر والاحساء والقطيف كذكل شركة تنظيف خزانات بجدة وتنظيف بجدة ومكافحة الحشرات بالخبر وكشف تسربات المياه بالجبيل والقطيف والخبر والدمام
http://emc-mee.com/tanks-cleaning-company-jeddah.html شركة تنظيف خزانات بجدة
http://emc-mee.com/water-leaks-detection-isolate-company-dammam.html شركة كشف تسربات المياه بالدمام
http://emc-mee.com/anti-insects-company-dammam.html شركة مكافحة حشرات بالدمام
http://emc-mee.com/tanks-cleaning-company-jeddah.html شركة تنظيف خزانات بجدة
http://emc-mee.com/ شركة نقل عفش واثاث
http://emc-mee.com/movers-in-riyadh-company.html شركة نقل اثاث بالرياض
http://emc-mee.com/transfer-furniture-jeddah.html شركة نقل عفش بجدة
http://emc-mee.com/transfer-furniture-dammam.html شركة نقل عفش بالدمام
http://emc-mee.com/transfer-furniture-almadina-almonawara.html شركة نقل عفش بالمدينة المنورة
http://emc-mee.com/transfer-furniture-taif.html شركة نقل عفش بالطائف
http://emc-mee.com/transfer-furniture-mecca.html شركة نقل عفش بمكة
اهم شركات نقل العفش والاثاث بالدمام والخبر والجبيل اولقطيف والاحساء والرياض وجدة ومكة المدينة المنورة والخرج والطائف وخميس مشيط وبجدة افضل شركة نقل عفش بجدة نعرضها مجموعة الفا لنقل العفش بمكة والخرج والقصيم والطائف وتبوك وخميس مشيط ونجران وجيزان وبريدة والمدينة المنورة وينبع افضل شركات نقل الاثاث بالجبيل والطائف وخميس مشيط وبريدة وعنيزو وابها ونجران المدينة وينبع تبوك والقصيم الخرج حفر الباطن والظهران

http://emc-mee.com/transfer-furniture-yanbu.html شركة نقل عفش بينبع
http://emc-mee.com/transfer-furniture-buraydah.html شركة نقل عفش ببريدة
http://emc-mee.com/transfer-furniture-alkharj.html شركة نقل عفش بالخرج
http://emc-mee.com/transfer-furniture-qassim.html شركة نقل عفش بالقصيم
http://emc-mee.com/transfer-furniture-khamis-mushait.html شركة نقل عفش بخميس مشيط
http://emc-mee.com/transfer-furniture-tabuk.html شركة نقل عفش بتبوك
http://emc-mee.com/transfer-furniture-abha.html شركة نقل عفش بابها
http://emc-mee.com/transfer-furniture-najran.html شركة نقل عفش بنجران
http://emc-mee.com/transfer-furniture-hail.html شركة نقل عفش بحائل
http://emc-mee.com/transfer-furniture-dhahran.html شركة نقل عفش بالظهران
http://emc-mee.com/transfer-furniture-kuwait.html شركة نقل عفش بالكويت

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author avatar شركة نقل اثاث بمكة
12th Jan 2020 (#)




http://jumperads.com/ نقل الاثاث
http://jumperads.com/transfer-furniture-riyadh.html شركة نقل عفش بالرياض
http://jumperads.com/transfer-furniture-jeddah.html شركة نقل عفش بجدة
http://jumperads.com/transfer-furniture-dammam.html شركة نقل عفش بالدمام
http://jumperads.com/transfer-furniture-medina-almonawara.html شركة نقل عفش بالمدينة المنورة
http://jumperads.com/transfer-furniture-taif.html شركة نقل عفش بالطائف
http://jumperads.com/transfer-furniture-mecca.html شركة نقل عفش بمكة
http://jumperads.com/transfer-furniture-yanbu.html شركة نقل عفش بينبع
http://jumperads.com/transfer-furniture-in-najran.html شركة نقل عفش بنجران
http://jumperads.com/transfer-furniture-in-khamis-mushait.html شركة نقل عفش بخميس مشيط
http://jumperads.com/transfer-furniture-abha.html شركة نقل عفش بابها
http://jumperads.com/transfer-furniture-buraydah.html شركة نقل عفش ببريدة
http://jumperads.com/transfer-furniture-qassim.html شركة نقل عفش بالقصيم
http://jumperads.com/transfer-furniture-tabuk.html شركة نقل عفش بتبوك
http://jumperads.com/transfer-furniture-hail.html شركة نقل عفش بحائل
http://jumperads.com/transfer-furniture-dammam-khobar.html شركة نقل عفش بالخبر
http://jumperads.com/transfer-furniture-ahsa.html شركة نقل عفش بالاحساء
http://jumperads.com/transfer-furniture-qatif.html شركة نقل عفش بالقطيف
http://jumperads.com/transfer-furniture-jubail.html شركة نقل عفش بالجبيل

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author avatar شركة سكاي لنقل العفش
12th Jan 2020 (#)




شركة سكاي لخدمات نقل العفش والاثاث بالمنطقة العربية السعودية نحن نوفر خدمات نقل اثاث بالرياض ونقل عفش بالمدينة المنورة ونقل عفش بمكة ونقل عفش بالطائف نحن نقدم افضل نقل اثاث بخميس مشيط ونقل عفش بجدة

http://treeads.net/ شركة سكاي لنقل العفش
http://treeads.net/movers-mecca.html نقل عفش بمكة
http://treeads.net/movers-riyadh-company.html نقل عفش بالرياض
http://treeads.net/all-movers-madina.html نقل عفش بالمدينة المنورة
http://treeads.net/movers-jeddah-company.html نقل عفش بجدة
http://treeads.net/movers-taif.html نقل عفش بالطائف
http://treeads.net/movers-dammam-company.html نقل عفش بالدمام
http://treeads.net/movers-qatif.html نقل عفش بالقطيف
http://treeads.net/movers-jubail.html نقل عفش بالجبيل
http://treeads.net/movers-khobar.html نقل عفش بالخبر
http://treeads.net/movers-ahsa.html نقل عفش بالاحساء
http://treeads.net/movers-kharj.html نقل عفش بالخرج
http://treeads.net/movers-khamis-mushait.html نقل عفش بخميس مشيط
http://treeads.net/movers-abha.html نقل عفش بابها
http://treeads.net/movers-qassim.html نقل عفش بالقصيم
http://treeads.net/movers-yanbu.html نقل عفش بينبع
http://treeads.net/movers-najran.html نقل عفش بنجران
http://treeads.net/movers-hail.html نقل عفش بحائل
http://treeads.net/movers-buraydah.html نقل عفش ببريدة
http://treeads.net/movers-tabuk.html نقل عفش بتبوك
http://treeads.net/movers-dhahran.html نقل عفش بالظهران
http://treeads.net/movers-rabigh.html نقل عفش برابغ
http://treeads.net/movers-baaha.html نقل عفش بالباحه
http://treeads.net/movers-asseer.html نقل عفش بعسير
http://treeads.net/movers-mgmaa.html نقل عفش بالمجمعة
http://treeads.net/movers-sharora.html نقل عفش بشرورة
http://treeads.net/movers-najran.html

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author avatar شركة نقل عفش بالمدينة المنو
12th Jan 2020 (#)


http://www.domyate.com/2015/08/30/furniture-transport-company-in-almadinah شركة نقل عفش بالمدينة المنورة
http://www.domyate.com/2016/06/05/transfer-furniture-medina-almonawara شركة نقل عفش بالمدينة المنورة
http://www.domyate.com/2016/06/05/transfer-furniture-mecca شركة نقل عفش بمكة
http://www.domyate.com/2016/06/05/transfer-furniture-riyadh شركة نقل عفش بالرياض
http://www.domyate.com/2016/06/05/transfer-furniture-jeddah شركة نقل عفش بجدة
http://www.domyate.com/2016/06/05/transfer-furniture-taif شركة نقل عفش بالطائف
http://www.domyate.com/2016/06/05/transfer-furniture-yanbu شركة نقل عفش بينبع
http://www.domyate.com/2016/07/02/transfer-furniture-dammam شركة نقل عفش بالدمام
http://www.domyate.com/2017/08/10/movers-company-mecca-naql/
http://www.domyate.com شركة نقل عفش بالدمام

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author avatar شركة كيان لنقل العفش
12th Jan 2020 (#)




شركة كيان لنقل العفش بالرياض والمدينة المنورة وجدة ومكة والطائف والدمام تقديم لكم دليل كامل لشركات نقل العفش بالمملكة العربية السعودية
http://mycanadafitness.com/ شركة كيان لنقل العفش
http://mycanadafitness.com/forum.html منتدي نقل العفش
http://mycanadafitness.com/movingfurnitureriyadh.html شركة نقل اثاث بالرياض
http://mycanadafitness.com/movingfurniturejaddah.html شركة نقل اثاث بجدة
http://mycanadafitness.com/movingfurnituremecca.html شركة نقل اثاث بمكة
http://mycanadafitness.com/movingfurnituretaif.html شركة نقل اثاث بالطائف
http://mycanadafitness.com/movingfurnituremadina.html شركة نقل اثاث بالمدينة المنورة
http://mycanadafitness.com/movingfurnituredammam.html شركة نقل اثاث بالدمام
http://mycanadafitness.com/movingfurniturekhobar.html شركة نقل اثاث بالخبر
http://mycanadafitness.com/movingfurnituredhahran.html شركة نقل اثاث بالظهران
http://mycanadafitness.com/movingfurniturejubail.html شركة نقل اثاث بالجبيل
http://mycanadafitness.com/movingfurnitureqatif.html شركة نقل اثاث بالقطيف
http://mycanadafitness.com/movingfurnitureahsa.html شركة نقل اثاث بالاحساء
http://mycanadafitness.com/movingfurniturekharj.html شركة نقل اثاث بالخرج
http://mycanadafitness.com/movingfurniturekhamismushit.html شركة نقل اثاث بخميس مشيط
http://mycanadafitness.com/movingfurnitureabha.html شركة نقل اثاث بابها
http://mycanadafitness.com/movingfurniturenajran.html شركة نقل اثاث بنجران
http://mycanadafitness.com/movingfurniturejazan.html شركة نقل اثاث بجازان
http://mycanadafitness.com/movingfurnitureasir.html شركة نقل اثاث بعسير
http://mycanadafitness.com/movingfurniturehail.html شركة نقل اثاث بحائل
http://mycanadafitness.com/movingfurnitureqassim.html شركة نقل عفش بالقصيم
http://mycanadafitness.com/movingfurnitureyanbu.html شركة نقل اثاث بينبع
http://mycanadafitness.com/movingfurnitureburaidah.html شركة نقل عفش ببريدة
http://mycanadafitness.com/movingfurniturehafralbatin.html شركة نقل عفش بحفر الباطن
http://mycanadafitness.com/movingfurniturerabigh.html شركة نقل عفش برابغ
http://mycanadafitness.com/movingfurnituretabuk.html شركة نقل عفش بتبوك
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http://mycanadafitness.com/movingfurnituresharora.html شركة نقل عفش بشرورة
http://mycanadafitness.com/companis-moving-riyadh.html شركات نقل العفش بالرياض
http://mycanadafitness.com/cars-moving-riyadh.html سيارات نقل العفش بالرياض
http://mycanadafitness.com/company-number-moving-riyadh.html ارقام شركات نقل العفش بالرياض
http://mycanadafitness.com/company-moving-jeddah.html شركات نقل العفش بجدة
http://mycanadafitness.com/price-moving-jeddah.html اسعار نقل العفش بجدة
http://mycanadafitness.com/company-moving-mecca.html شركات نقل العفش بمكة

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author avatar شركة ريلاكس لنقل العفش والا
12th Jan 2020 (#)


http://fullservicelavoro.com/ شركة ريلاكس لنقل العفش والاثاث
http://fullservicelavoro.com/2019/01/07/transfer-movers-taif-furniture/ شركة نقل عفش بالطائف
http://fullservicelavoro.com/2019/01/08/transfer-movers-riyadh-furniture/ شركة نقل عفش بالرياض
http://fullservicelavoro.com/2019/01/08/transfer-movers-jeddah-furniture/ شركة نقل عفش بجدة
http://fullservicelavoro.com/2019/01/01/transfer-and-movers-furniture-mecca/ شركة نقل عفش بمكة
http://fullservicelavoro.com/2019/01/07/transfer-movers-madina-furniture/ شركة نقل عفش بالمدينة المنورة
http://fullservicelavoro.com/2019/01/07/transfer-movers-khamis-mushait-furniture/ شركة نقل عفش بخميس مشيط
http://fullservicelavoro.com/2019/01/09/transfer-movers-abha-furniture/ شركة نقل اثاث بابها
http://fullservicelavoro.com/2019/01/07/transfer-movers-najran-furniture/ شركة نقل عفش بنجران
http://fullservicelavoro.com/2019/01/16/transfer-movers-hail-furniture/ ِشركة نقل عفش بحائل
http://fullservicelavoro.com/2019/01/16/transfer-movers-qassim-furniture/ شركة نقل عفش بالقصيم
http://fullservicelavoro.com/2019/02/02/transfer-movers-furniture-in-bahaa/ شركة نقل عفش بالباحة
http://fullservicelavoro.com/2019/01/13/transfer-movers-yanbu-furniture/ شركة نقل عفش بينبع
http://fullservicelavoro.com/2019/01/18/%d8%af%d9%8a%d9%86%d8%a7-%d9%86%d9%82%d9%84-%d8%b9%d9%81%d8%b4-%d8%a8%d8%a7%d8%a8%d9%87%d8%a7/ دينا نقل عفش بابها
http://fullservicelavoro.com/2019/01/13/%D9%86%D9%82%D9%84-%D8%A7%D9%84%D8%A7%D8%AB%D8%A7%D8%AB-%D8%A8%D8%A7%D9%84%D9%85%D8%AF%D9%8A%D9%86%D8%A9-%D8%A7%D9%84%D9%85%D9%86%D9%88%D8%B1%D8%A9-%D8%A7%D9%87%D9%85-%D8%B4%D8%B1%D9%83%D8%A7%D8%AA/ نقل الاثاث بالمدينة المنورة
http://fullservicelavoro.com/2019/01/12/%D8%A7%D8%B1%D8%AE%D8%B5-%D8%B4%D8%B1%D9%83%D8%A9-%D9%86%D9%82%D9%84-%D8%B9%D9%81%D8%B4-%D8%A8%D9%85%D9%83%D8%A9/ ارخص شركة نقل عفش بمكة
http://fullservicelavoro.com/2019/01/07/transfer-movers-elkharj-furniture/ شركة نقل عفش بالخرج
http://fullservicelavoro.com/2019/01/07/transfer-movers-baqaa-furniture/ شركة نقل عفش بالبقعاء
http://fullservicelavoro.com/2019/02/05/transfer-furniture-in-jazan/ شركة نقل عفش بجازان

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author avatar شركة تنظيف بالطائف
12th Jan 2020 (#)



http://emc-mee.3abber.com/ شركات نقل وتنظيف
http://emc-mee.3abber.com/post/338152 شركات نقل عفش بالطائف
http://emc-mee.3abber.com/post/338038 شركات نقل عفش بالمدينة المنورة
http://emc-mee.3abber.com/post/338040 شركات نقل عفش بمكة
http://emc-mee.3abber.com/post/338301 شركات نقل عفش
http://emc-mee.3abber.com/post/338302 شركة تنظيف خزانات بالمدينة المنورة
http://emc-mee.3abber.com/post/338181 شركات تنظيف بمكة
http://emc-mee.3abber.com/post/338037 شركة مكافحة حشرات
http://emc-mee.3abber.com/post/338031 شركة تنظيف بالدمام
http://emc-mee.3abber.com/post/338030 شركة تنظيف بالمدينة
http://emc-mee.3abber.com/post/338028 شركة تنظيف بالطائف
https://www.behance.net/gallery/46472895/_
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https://www.behance.net/gallery/40396873/Transfer-and-relocation-and-Furniture-in-Dammam
http://kenanaonline.com/east-eldmam
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